发明名称 |
Adjuvant-containing vaccines |
摘要 |
This invention provides a DNA vaccine which comprises a naked DNA incorporating and expressing in vivo a nucleotide sequence encoding an antigenic polypeptide, preferably a gene of a pathogenic agent, and at least one adjuvant compound chosen from the polymers of acrylic or methacrylic acid and copolymers of maleic anhydride and alkenyl derivative. The adjuvant compound is preferably a carbomer or an EMA(R). This invention also provides a method of enhancing a DNA vaccine and/or the immunogenicity of a DNA vaccine. |
申请公布号 |
AU2844899(A) |
申请公布日期 |
1999.10.25 |
申请号 |
AU19990028448 |
申请日期 |
1999.03.22 |
申请人 |
MERIAL |
发明人 |
JEAN-CHRISTOPHE FRANCIS AUDONNET;JULES MAARTEN MINKE |
分类号 |
A61K48/00;A61K39/39;A61P31/12;A61P37/04 |
主分类号 |
A61K48/00 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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