A PROCESS FOR THE PREPARATION OF AMLODIPINE BENZENESULPHONATE

摘要

A process for the preparation of amlodipine benzenesulphonate is disclosed, wherein a salt of amlodipine with an inorganic or organic acid is reacted with alkali metal benzenesulphonate in an aqueous medium or in a mixture water-alcohol C1-C2. Amlodipine benzenesulphonate is used for the preparation of a medicament having calcium channel blocking activity, useful in the treatment of the coronary disease and arterial hypertension.