Disclosed are 3'-N-desmethyl-3'-N-substituted-6-O-methyl-11-deoxy-11,12-cyclic carbamate erythromycin A derivatives which are antagonists of lutenizing hormone-releasing hormone (LHRH). Also disclosed are pharmaceutical compositions comprising the compounds, to methods of using the compounds and to the process of making the same.
申请公布号
US5955440(A)
申请公布日期
1999.09.21
申请号
US19980049963
申请日期
1998.03.27
申请人
ABBOTT LABORATORIES
发明人
SAUER, DARYL R.;HAVIV, FORTUNA;RANDOLPH, JOHN;MORT, NICHOLAS A.;DALTON, CHRISTOPHER R.;BRUNCKO, MILAN;KAMINSKI, MICHELE A.;CRAWFORD, BRADLEY W.;FREY, LISA MARIE;GREER, JONATHAN