发明名称 |
(vibrio cholerae) vaccine candidates and method of their constructing |
摘要 |
Vibrio cholerae vaccine strains which have a disrupted hap gene and which are tagged with celA coding functions from Clostridium thermocellum are described. A contained, genetically defined thyA mutant of Vibrio cholerae and the general methodology of making along with the sequence of thyA gene are also described. |
申请公布号 |
AU1959199(A) |
申请公布日期 |
1999.07.26 |
申请号 |
AU19990019591 |
申请日期 |
1998.12.30 |
申请人 |
CENTRO NACIONAL DE INVESTIGACIONES CIENTIFICAS |
发明人 |
JAVIER CAMPOS GOMEZ;RAFAEL ALFREDO FANDO CALZADA;BORIS LUIS RODRIGUEZ GONZALEZ;TALENA YAMILE LEDON PEREZ;EDGAR VALLE DIAZ;ANISIA JUANA SILVA CABRERA;JORGE ANTONIO BENITEZ ROBLES |
分类号 |
C12N15/09;A61K39/106;A61P31/04;C12N1/21;C12N9/10;C12N9/52;C12N15/31;C12R1/63 |
主分类号 |
C12N15/09 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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