发明名称 |
Bis mono- and bicyclic aryl and heteroaryl compounds which inhibit EGF and/or PDGF receptor tyrosine kinase |
摘要 |
This invention relates to bis mono- and/or bicyclic aryl and/or heteroaryl compounds exhibiting protein tyrosine kinase inhibition activity. More specifically, it relates to the method of inhibiting abnormal cell proliferation in a patient suffering from a disorder characterized by such proliferation comprising the administration thereto of an EGF and/or PDGF receptor inhibiting effective amount of said bis mono- and/or bicyclic aryl and/or heteroaryl compound and to the preparation of said compounds and their use in pharmaceutical compositions used in this method.
|
申请公布号 |
USRE36256(E) |
申请公布日期 |
1999.07.20 |
申请号 |
US19970988005 |
申请日期 |
1997.12.10 |
申请人 |
RHONE-POULENC RORER PHARMACEUTICALS, INC. |
发明人 |
SPADA, ALFRED P.;MYERS, MICHAEL R.;MAGUIRE, MARTIN P.;PERSONS, PAUL E. |
分类号 |
A61K31/495;A61K31/535;C07D241/52;C07D241/54;(IPC1-7):A61K31/495 |
主分类号 |
A61K31/495 |
代理机构 |
|
代理人 |
|
主权项 |
|
地址 |
|