发明名称 Bis mono- and bicyclic aryl and heteroaryl compounds which inhibit EGF and/or PDGF receptor tyrosine kinase
摘要 This invention relates to bis mono- and/or bicyclic aryl and/or heteroaryl compounds exhibiting protein tyrosine kinase inhibition activity. More specifically, it relates to the method of inhibiting abnormal cell proliferation in a patient suffering from a disorder characterized by such proliferation comprising the administration thereto of an EGF and/or PDGF receptor inhibiting effective amount of said bis mono- and/or bicyclic aryl and/or heteroaryl compound and to the preparation of said compounds and their use in pharmaceutical compositions used in this method.
申请公布号 USRE36256(E) 申请公布日期 1999.07.20
申请号 US19970988005 申请日期 1997.12.10
申请人 RHONE-POULENC RORER PHARMACEUTICALS, INC. 发明人 SPADA, ALFRED P.;MYERS, MICHAEL R.;MAGUIRE, MARTIN P.;PERSONS, PAUL E.
分类号 A61K31/495;A61K31/535;C07D241/52;C07D241/54;(IPC1-7):A61K31/495 主分类号 A61K31/495
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