NOVEL GUANOSINE TRIPHOSPHATE (GTP) BINDING PROTEIN-COUPLED RECEPTOR PROTEIN

摘要

A full-length cDNA encoding a rat G protein conjugate type receptor protein which is isolated by screening cDNA libraries originating in rat thalamus and hypothalamus; and human cDNA corresponding to the above rat cDNA. Use of these G protein conjugate type receptor proteins makes it possible to screen ligands and to screen compounds which are candidates for drugs capable of regulating signal transduction from receptors.