VERFAHREN TUR LIPOSOMENHERSTELLUNG OHNE VERWENDUNG ORGANISCHER LOESUNGSMITTEL

摘要

PCT No. PCT/FR95/00012 Sec. 371 Date Jul. 31, 1996 Sec. 102(e) Date Jul. 31, 1996 PCT Filed Jan. 5, 1995Multilamellar lipid vesicles are prepared by a two-step method. In the first step, a sterol is completely dissolved in a mixture comprising an aqueous solvent and a surfactant. In the second step, a lipid surfactant is added to a solution resulting from the first step, to prepare a homogeneous lamellar liquid crystal phase or a liquid crystal phase suspension in water. The liquid crystal phase or liquid crystal phase suspension can then be converted into multilamellar lipid vesicles.