Process for the preparation of 1-amino-1-methyl-3(4)-aminomethyl cyclohexane

摘要

The present invention relates to a process for the preparation of 1-amino-1-methyl-3(4)-aminomethyl cyclohexane (AMCA) by a) catalytically hydrogenating 1-formamido-1-methyl-3(4)-cyano cyclohexane (FMC) in a first reaction stage to form 1-formamido-1-methyl-3(4)-aminomethyl cyclohexane (FMA), 1-amino-1-methyl-3(4)-formamidomethyl cyclohexane (AMF), 1-formamido-1-methyl-3(4)-formamidomethyl cyclohexane (FMF) and/or AMCA, and b) reacting FMA, AMF and/or FMF in a second reaction stage with an alkaline compound to from AMCA and a formic acid derivative, and c) separating the reaction mixture obtained in step b) into components by fractional distillation and/or by crystallization and filtration. The present invention is also relates to carrying the hydrogenation reaction of step a) in the presence of a formulating agent to form 1-formamido-1-methyl-3(4)-formamidomethyl cyclohexane (FMF). Finally, the present invention relates to the intermediate products 1-formamido-1-methyl-3(4)-aminomethyl cyclohexane (FMA) and 1-formamido-1-methyl-3(4)-formamidomethyl cyclohexane (FMF).