| 发明名称 |
INHIBITORS OF FARNESYL PROTEIN TRANSFERASE |
| 摘要 |
Inhibition of farnesyl transferase, which is an enzyme involved in ras oncogene expression, is effected by compounds of formulas (I), (II), their enantiomers, diastereomers, and pharmaceutically acceptable salts, prodrugs and solvates thereof inhibit farnesyl protein transferase which is an enzyme involved in ras oncogene expression.
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| 申请公布号 |
WO9918951(A1) |
申请公布日期 |
1999.04.22 |
| 申请号 |
WO1998US19315 |
申请日期 |
1998.09.16 |
| 申请人 |
BRISTOL-MYERS SQUIBB COMPANY |
发明人 |
DING, CHARLES, Z.;HUNT, JOHN, T.;LEFTHERIS, KATERINA;BHIDE, RAJEEV, S. |
| 分类号 |
A61K31/551;A61K31/5513;A61P35/00;A61P43/00;C07D243/12;C07D243/14;C07D401/06;C07D401/12;C07D403/06;C07D403/12;C07D409/06;(IPC1-7):A61K31/33;A61K31/495;A61K31/50;A61K31/53;A61K31/535;A61K31/54;A61K31/55;C07D237/26;C07D239/70;C07D241/36;C07D245/04;C07D249/16;C07D251/72;C07D253/08;C07D257/10;C07D261/20;C07D263/52;C07D265/02;C07D265/12;C07D265/28;C07D271/12;C07D273/02;C07D275/04;C07D277/60;C07D279/14;C07D291/08 |
主分类号 |
A61K31/551 |
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