Method of identification of leads or active compounds

摘要

The invention relates to methods of selection of leads or active compounds from libraries. More specifically, the invention provides methods of selection of leads or compounds which are active and selective towards a desired target. In particular, the invention provides a screening method for the identification of leads from a library of compounds, said method comprising the steps of : (a) screening a library of compounds for activity against a desired target, to obtain potent hits; (b) profiling the potent hits of step (a) to obtain potent and selective leads. The instant invention can be used for instance in drug discovery processes.