| 摘要 |
PROBLEM TO BE SOLVED: To produce the subject compound useful as intermediate for important pharmaceuticals, intermediate for important agrochemicals, raw material for photosensitive material for resist, etc., by reacting cyclohexanone with chlorine in the presence of a catalyst in a liquid phase under specific condition. SOLUTION: 2,2,6,6-Tetrachlorocyclohexanone is produced by reacting 1 mol of cyclohexanone with preferably 4.2-4.5 mol of chlorine preferably in a solvent (e.g. chlorobenzene) at 60-120 deg.C in the presence of preferably 0.5-5.0 mol.% of a catalyst (e.g. pyridine or triphenylphosphine) in liquid phase while supplying the cyclohexanone preventing the contact with the by-produced hydrogen chloride gas. The cyclohexanone is supplied e.g. directly into the liquid phase e.g. by supplying cyclohexanone into a circulation line of a reaction system consisting of a reactor, a circulation apparatus and a circulation line connecting the apparatuses. |
