发明名称 |
All-trans-retinol metabolite |
摘要 |
In vitro incubation of all-trans-retinol (atROL) with kidney homogenate from vitamin A deficient and retinoic acid supplemented (VAD-RAS) female rats produced a new retinol metabolite. The metabolite has the structure <IMAGE> and is believed useful for the treatment of skin disorders such as acne, psoriasis, and ultraviolet light skin damage, as well as for promoting female fertility and the maintenance of pregnancy.
|
申请公布号 |
US5880292(A) |
申请公布日期 |
1999.03.09 |
申请号 |
US19970927511 |
申请日期 |
1997.09.11 |
申请人 |
WISCONSIN ALUMNI RESEARCH FOUNDATION |
发明人 |
DELUCA, HECTOR F.;SCHNOES, HEINRICH K.;SICINSKI, RAFAL R.;JIA, XIUJUAN |
分类号 |
C07D333/22;(IPC1-7):C07D333/10;A61K31/38 |
主分类号 |
C07D333/22 |
代理机构 |
|
代理人 |
|
主权项 |
|
地址 |
|