Benzo(b)thiophene derivatives for inhibiting detrimental side-effects due to GnRH or GnRH agonist administration

摘要

The use of a compound of formula I <CHEM> wherein R<1> and R<3> are, independently, -H, -CH3, -CO(C1-C6 alkyl), or -COAr, where Ar is optionally substituted phenyl; R<3> is selected from the group consisting of pyrrolidine, piperidine, and hexamethyleneimino; or a pharmaceutically acceptable salt or solvate thereof, in the preparation of a pharmaceutical formulation for inhibiting detrimental side-effects of GnRH or a GnRH agonist in a mammal.