摘要 |
Aminocycloalkane compounds represented by general formula (I) or pharmacologically acceptable salts thereof wherein Ar represents optionally substituted phenyl or thienyl; X represents cyano or carbamoyl; R1 and R2 each independently represents hydrogen, lower alkyl, etc. or R1 and R2 together with the nitrogen atom bonded thereto represent (II) (wherein R3 represents hydrogen, lower alkyl, etc.); and m is 2, 3, or 4. The compounds have a highly selective antagonistic action on a muscarine M3 receptor.
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申请人 |
TOKYO TANABE COMPANY LIMITED;OHNO, NORIO;NAKANO, MASAKAZU;ENDOH, JUN-ICHI;MIURA, MASATAKA;AIZAWA, HIDEYUKI;FUKUZAKI, ATHUSHI;SEIDA, KEIICHI |
发明人 |
OHNO, NORIO;NAKANO, MASAKAZU;ENDOH, JUN-ICHI;MIURA, MASATAKA;AIZAWA, HIDEYUKI;FUKUZAKI, ATHUSHI;SEIDA, KEIICHI |