| 发明名称 |
Humanized monoclonal antibodies against human interleukin-4 |
| 摘要 |
PCT No. PCT/US93/01301 Sec. 371 Date Aug. 16, 1994 Sec. 102(e) Date Aug. 16, 1994 PCT Filed Feb. 18, 1993 PCT Pub. No. WO93/17106 PCT Pub. Date Sep. 2, 1993Monoclonal antibodies are provided which are specific for human interleukin-4. Also provided are complementary DNAs which encode the heavy and light chain variable regions of such monoclonal antibodies and complementarity determining regions from such DNAs; and kits and methods for detecting, measuring and immunopurifying human interleukin-4, and for blocking the biological activity of human interleukin-4.
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| 申请公布号 |
US5863537(A) |
申请公布日期 |
1999.01.26 |
| 申请号 |
US19940290793 |
申请日期 |
1994.08.16 |
| 申请人 |
SCHERING CORPORATION |
发明人 |
DALIE, BARBARA;LE, HUNG V.;MILLER, KENNETH;MURGOLO, NICHOLAS J.;NGUYEN, HANH;TINDALL, STEPHEN;ZAVODNY, PAUL J. |
| 分类号 |
A61K38/00;A61K39/395;A61P43/00;C07K14/47;C07K14/52;C07K14/54;C07K16/00;C07K16/24;C07K16/46;C12N5/10;C12N15/02;C12N15/09;C12N15/13;C12P21/02;C12P21/08;C12R1/91;(IPC1-7):A61K39/395;A61K39/40 |
主分类号 |
A61K38/00 |
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