Fremgangsmåder og reagenser til HLA DRbeta-DNA-typebestemmelse
摘要
<p>Primers for amplification of specific nucleic acid sequences of the second exon of HLA DRbeta genes and probes for identifying polymorphic sequences contained in the amplified DNA can be used in processes for typing homozygous or heterozygous samples from a variety of sources and for detecting allelic variants not distinguishable by serological methods. This HLA DRbeta DNA typing system can be used in a dotblot format that is simple and rapid to perform, produces detectable signals in minutes, and can be used for tissue typing, determining individual identity, and identifying disease susceptible individuals.</p>
申请公布号
DK0514534(T3)
申请公布日期
1999.01.11
申请号
DK19920902641T
申请日期
1991.12.06
申请人
F. HOFFMANN-LA ROCHE AG
发明人
ERLICH, HENRY, A.;BEGOVICH, ANN, B.;BUGAWAN, TEODORICA;GRIFFITH, ROBERT, L.;SCHARF, STEPHEN, J.;APPLE, RAYMOND, J.