| 发明名称 |
FUMARATE SALT OF (R)-5-(METHYLAMINOSULFONYL-METHYL)-3-(N- -METHYLPYROLIDIN-2-YLMETHYL)-1H-INDOLE, PREPARATION AND USE THEREOF AND PHARMACEUTICAL COMPOSITION |
| 摘要 |
Disclosed is a fumarate salt (R)-5-(methyl-amino-sulphonyl- methyl)-3-(N-methyl-pyrolidine-2-ylmethyl)-1H-indole. This salt is preparated by reaction of free base with fumaric acid. Pharmaceutical composition containing said fumarate salt and pharmaceutically acceptable diluent or carrier. Using of this salt to produce medicament and for treatment of migraine.
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| 申请公布号 |
SK154197(A3) |
申请公布日期 |
1999.01.11 |
| 申请号 |
SK19970001541 |
申请日期 |
1996.04.10 |
| 申请人 |
PFIZER RESEARCH AND DEVELOPMENT COMPANY N.V./S.A |
发明人 |
WYTHES MARTIN J. |
| 分类号 |
A61K31/40;A61K31/4045;A61P25/04;A61P25/06;C07D403/06;(IPC1-7):C07D403/06 |
主分类号 |
A61K31/40 |
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