发明名称 |
Compositions and methods of developing oligonucleotides and oligonucleotide analogs having antiviral activity |
摘要 |
Methods of identifying and preparing anti-infectious agent compounds comprising the steps of incubating single stranded nucleic acids or nucleic acid analogs in the presence of infectious agents, selecting for nucleic acids or nucleic acid analogs which bind infectious agents, amplifying selected nucleic acids or nucleic acid analogs, repeating the selection steps and assaying for anti-infection activity are disclosed. Compositions that have anti-infectious activity against Rous sarcoma virus are also disclosed. Methods of identifying anti-tumor agent compounds are also disclosed.
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申请公布号 |
US5856085(A) |
申请公布日期 |
1999.01.05 |
申请号 |
US19950566216 |
申请日期 |
1995.12.01 |
申请人 |
THE PENN STATE RESEARCH FOUNDATION |
发明人 |
WANG, JIN-FENG;PAN, WEIHUA |
分类号 |
C12Q1/68;(IPC1-7):C12Q1/70;C12P19/34;C07H21/02 |
主分类号 |
C12Q1/68 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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