PRENYLCYSTEINE CARBOXYL METHYLTRANSFERASE, DNA ENCODING SAME, AND A METHOD OF SCREENING FOR INHIBITORS THEREOF

摘要

A mammalian protein, prenylcysteine carboxyl methyltransferase, involved in further post-translational modification of prenylated proteins, is cloned, characterized, and expressed in non-native cells. Such membrane preparations can be used to screen for inhibitors of prenylcysteine carboxyl methyltransferase activity.