Tertiary-alkylamino-lower acyl-xylidide local anaesthetics
摘要
Tertiary-alkylamino-lower acyl-xylidides have unusually long lasting local anaesthetic effect or high local anaesthetic activity while also having a satisfactory low level of tissue irritation and a satisfactory low acute toxicity. Combinations of such local anaesthetics with the biotoxins tetrodotoxin or saxitoxin are disclosed. Novel tertiary alkyl secondary amines, and methods for preparing such local anaesthetics and amines are also disclosed.
申请公布号
US3988473(A)
申请公布日期
1976.10.26
申请号
US19750561604
申请日期
1975.03.24
申请人
ASTRA PHARMACEUTICAL PRODUCTS, INC.
发明人
ADAMS, HERBERT J. F.;ANDERSON, JON C.;BLAIR, JR., MURRAY R.;DI RUBIO, ROBERT L.;TAKMAN, BERTIL H.