发明名称 |
Compositions and methods for diagnosing/treating disease based on beta-catenin/transcription factor interactions |
摘要 |
Methods and compositions are described that are useful for diagnosing and/or treating disease arising from unwanted cell growth, preferably cancer, involving diagnosing cells for stabilized beta-catenin, or treating cells with compounds that disrupt or alter the formation of a complex consisting of beta-catenin/transcription factor, where the transcription factor is a member of the Lef/Tcf family. |
申请公布号 |
AU6866198(A) |
申请公布日期 |
1998.10.20 |
申请号 |
AU19980068661 |
申请日期 |
1998.03.18 |
申请人 |
ONYX PHARMACEUTICALS, INC. |
发明人 |
PAUL POLAKIS;BONNEE RUBINFELD |
分类号 |
C12N15/09;A61K38/00;A61K45/00;A61P35/00;A61P43/00;C07K14/47 |
主分类号 |
C12N15/09 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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