摘要 |
PROBLEM TO BE SOLVED: To obtain the subject new compound capable of being used as an excellent fluorescent labeling reagent for separating and determining carboxylic acids by fluorescent detection-liquid chromatography. SOLUTION: A new fluorescent labeling agent, 4-[(ω-aminoalkyl)amino]-7-N,N- dimethylaminosulfonyl-2,1,3-benzoxadiazole of the formula [(n) is an integer of >=1]. The compound of formula I can easily obtained e.g. from 4-chloro-7-N, N-dimethylaminosulfonyl-2,1,3-benzoxadiazole and anα,ω-diaminoalkane. The compound of the formula has an amino group for moderately reacting and binding to a carboxyl group in the presence of a condensing agent, and a skeleton emitting strong fluorescent light long in both exciting light and fluorescent light wavelengths exhibits usefulness as a fluorescent light labeling reagent.
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