Methods and compositions for inhibiting cell proliferative disorders
摘要
The present invention concerns compounds and their use to inhibit the activity of a receptor tyrosine kinase. The invention is preferably used to treat cell proliferative disorders such as cancers charcterized by over-activity or inappropriate activity HER2 or EGFR.
申请公布号
US5773476(A)
申请公布日期
1998.06.30
申请号
US19950486775
申请日期
1995.06.07
申请人
SUGEN, INC.;YISSUM RESEARCH AND DEVELOPMENT COMPANY OF THE HEBREW UNIVERSITY OF JERUSALEM
发明人
CHEN, HUI;GAZIT, AVIV;LEVITZKI, ALEXANDER;HIRTH, KLAUS PETER;MANN, ELAINA;SHAWVER, LAURA K.;TSAI, JIANMING;TANG, PENG CHO