发明名称 METHOD FOR IMPROVED SELECTIVITY IN PHOTO-ACTIVATION AND DETECTION OF MOLECULAR DIAGNOSTIC AGENTS
摘要 A method for the imaging of a particular volume of plant or animal tissue, wherein the plant or animal tissue contains at least one photo-active molecular agent. The method comprises the steps of treating the particular volume of the plant or animal tissue with light sufficient to promote a simultaneous two-photon excitation of the photo-active molecular agent contained in the particular volume of the plant or animal tissue, photoactivating at least one of the photo-active molecular agents in the particular volume of the plant or animal tissue, thereby producing at least one photoactivated molecular agent, wherein the at least one photo-activated molecular agent emits energy, detecting the energy emitted by the at least one photoactivated molecular agent, and producing a detected energy signal which is characteristic of the particular volume of plant or animal tissue. The present invention also provides a method for the imaging of a particular volume of material, wherein the material contains at least one photo-active molecular agent.
申请公布号 CA2252782(A1) 申请公布日期 1998.05.07
申请号 CA19972252782 申请日期 1997.10.27
申请人 PHOTOGEN, INC. 发明人 FISHER, WALTER G.;DEES, H. CRAIG;WACHTER, ERIC A.
分类号 G01N21/64;A61B17/00;A61B19/00;A61K41/00;A61K49/00;(IPC1-7):A61B6/00;G01N21/84 主分类号 G01N21/64
代理机构 代理人
主权项
地址