摘要 |
FIELD: organic chemistry; medicine. SUBSTANCE: derivatives of aspartame have formula <EMI ID=0.144 HE=48 WI=36 TI=CHI> where R is chosen of <EMI ID=0.145 HE=12 WI=90 TI=CHI>, cyclohexyl, cycloheptyl. cyclooctyl, cyclopentylmethyl, cyclohexylmethyl, 3-phenyl propyl, 3-methyl-3-phenyl propyl, 3,3-dimethylcyclopentyl, 3-methylcyclohexyl, 3,3,5,5-tetramethylcyclohexyl, 2-hydroxycyclohexyl 3-[4-hydroxy-3-methoxyphenyl] -propyl, 3-[4-hydroxy-3-methoxyphenyl] -2-propenyl, 3-[4-hydroxy-3-methoxyphenyl]-1-methyl-2-propenyl; X is chosen of CH<SB>3</SB>,CH<SB>2</SB>CH<SB>3</SB>,CH(CH<SB>3</SB>)<SB>2</SB>,CH<SB>2</SB>CH<SB>2</SB>CH<SB>3</SB> and C(CH<SB>3</SB>)<SB>3</SB>; Z is hydrogen atom or OH-group. EFFECT: improved quality. 8 cl, 2 tbl, 2 dwgC |