The present invention concerns a novel member of the tumor necrosis factor (TNF) family of cytokines. In particular, isolated nucleic acid molecules are provided encoding the endokine alpha protein. Endokine alpha polypeptides are also provided, as are vectors, host cells and recombinant methods for producing the same. Also provided are diagnostic and therapeutic methods concerning TNF family-related disorders.
申请公布号
WO9807880(A1)
申请公布日期
1998.02.26
申请号
WO1996US13282
申请日期
1996.08.16
申请人
HUMAN GENOME SCIENCES, INC.;YU, GUO-LIANG;NI, JIAN;ROSEN, CRAIG, A.