Medicinal compositions for the improvement of blood coagulation comprising TCF-II

摘要

PCT No. PCT/JP93/00974 Sec. 371 Date Jan. 11, 1995 Sec. 102(e) Date Jan. 11, 1995 PCT Filed Jul. 14, 1993 PCT Pub. No. WO94/02165 PCT Pub. Date Feb. 3, 1994Blood coagulation normalizing agents comprising effective ingredient of TCF-II. The blood coagulation normalizing agents of the present invention comprised of glycoprotein TCF-II produced by human fibroblast cells and accelerates the production of blood coagulation factor and increases platelet count to treat abnormal blood coagulation such as disseminated intravascular coagulation (DIC) and decreased platelet count caused by administration of cisplatin.