发明名称 |
Automated electrophoresis and fluorescence detection apparatus and method |
摘要 |
Improved detection methods and apparatus which may be used individually or in various combinations enhance the ability of the electrophoresis apparatus to detect fluorophore-labeled materials in short periods of time. One such apparatus comprises a housing adapted to receive an electrophoresis gel holder; an excitation source of electromagnetic radiation having a frequency effective to induce emission of electromagnetic radiation from the fluorophore; a plurality of optical fibers for delivering electromagnetic radiation from the excitation source to a linear array of excitation/detection sites on the gel holder, optical switching means for sequentially directing electromagnetic radiation into one of several pre-defined groups of the optical fibers; detection means such as a photomultiplier tube, or an array of photomultiplier tubes for detecting emission from the fluorophore induced by a radiation from the excitation source; and means for correlating a detected emission with the switching of the excitation electromagnetic radiation such that a given emission may be linked with the excitation/detection site being irradiated.
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申请公布号 |
US5710628(A) |
申请公布日期 |
1998.01.20 |
申请号 |
US19940353932 |
申请日期 |
1994.12.12 |
申请人 |
VISIBLE GENETICS INC. |
发明人 |
WATERHOUSE, PAUL;RENFREW, JOHN A.;STEVENS, JOHN K. |
分类号 |
G01N21/64;G01N27/447;(IPC1-7):G01N21/00 |
主分类号 |
G01N21/64 |
代理机构 |
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主权项 |
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地址 |
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