| 发明名称 |
Use of persistent free-radicals in magnetic resonance imaging |
| 摘要 |
The present invention relates to the use of persistent free radicals, in particular persistent free radicals having a carbon-based pi -bonded electronic system available for delocalization of the unpaired electrons as image enhancing agents in magnetic resonance imaging (MRI), in particular electron spin resonance enhanced magnetic resonance imaging (ESREMRI). The invention also relates to contrast media containing such radicals and to the use of such radicals and their non-radical precursors in the manufacture of MRI and ESREMRI contrast media.
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| 申请公布号 |
US5700448(A) |
申请公布日期 |
1997.12.23 |
| 申请号 |
US19950415662 |
申请日期 |
1995.04.03 |
| 申请人 |
NYCOMED IMAGING AS |
发明人 |
GOLMAN, KLAES;ANDERSSON, SVEN;RISE, FRODE;WISTRAND, LARS-GORAN;WIKSTROM, HAKAN |
| 分类号 |
A61B5/055;A61K;A61K49/00;A61K49/20;C07B60/00;C07C43/20;C07C45/67;C07C45/70;C07C46/00;C07C49/747;C07C49/753;C07C50/28;C07C69/92;C07C233/69;C07C235/48;C07C255/32;C07C255/36;C07C255/41;C07C309/66;C07C317/22;C07C317/24;C07C323/20;C07D209/36;C07D209/48;C07D215/24;C07D311/82;C07D339/06;C07D471/04;C07D493/04;C07D495/04;C07D497/04;C07D519/00;(IPC1-7):A61B5/055 |
主分类号 |
A61B5/055 |
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