Process for the crystallization from water of (S)-N,N'-bis[2-hydroxy-1-(hydroxymethyl)ethyl]-5-[2-hydroxy-1-oxopropyl)amino]-2,4,6-triiodo-1,3-benzendicarboxamide

摘要

This invention refers to a process for the crystallization from water of S-N,N'-bis[2-hydroxy-1(hydroxymethyl)ethyl]-5-[(2-hydroxy-1-oxopropyl)amino]-2,4,6-triiodo-1,3-benzendicarboxamide known as Iopamidol. According to the process of this invention, a crystalline anhydrous Iopamidol in accordance with pharmacopeia standards can be obtained.