发明名称 |
Steroidal glycosides for treating hypercholesterolemia |
摘要 |
<p>The invention provides spirostanyl glycosides of formula I,
<Chemistry id="chema01" num="0001"><Image id="ia01" he="42" wi="80" file="IMGA0001.TIF" imgContent="chem" imgFormat="TIFF" /></Chemistry> wherein
<UnorderedLists id="ula01" listStyle="none"><ListItem>Q<Sup>1</Sup>, Q<Sup>4</Sup> and Q<Sup>5</Sup> are each methylene;</ListItem><ListItem>Q<Sup>2</Sup> is
<Chemistry id="chema02" num="0002"><Image id="ia02" he="14" wi="43" file="IMGA0002.TIF" imgContent="chem" imgFormat="TIFF" /></Chemistry></ListItem><ListItem>Q<Sup>3</Sup> is
<Chemistry id="chema03" num="0003"><Image id="ia03" he="16" wi="122" file="IMGA0003.TIF" imgContent="chem" imgFormat="TIFF" /></Chemistry> and</ListItem><ListItem>R<Sup>1</Sup> is a specified glycosidic group.</ListItem></UnorderedLists></p><p>The comopunds are useful in the treatment of hypercholesterolemia or atherosclerosis.</p> |
申请公布号 |
EP0796863(A2) |
申请公布日期 |
1997.09.24 |
申请号 |
EP19970200455 |
申请日期 |
1993.05.06 |
申请人 |
PFIZER INC. |
发明人 |
DENINNO, MICHAEL PAUL;MCCARTHY, PETER ANDREW |
分类号 |
A61K31/58;A61K31/704;A61P3/06;A61P9/10;C07J71/00;(IPC1-7):C07J71/00 |
主分类号 |
A61K31/58 |
代理机构 |
|
代理人 |
|
主权项 |
|
地址 |
|