| 摘要 |
The invention provides an encapsulated cell system comprising at least one capsule, each capsule comprising a core containing a cellular source of a biologically active molecule and a surrounding biocompatible jacket, the jacket permitting diffusion of the biologically active molecule, wherein the biologically active molecule is selected from the group consisting of hormones, cytokines, growth factors, angiogenesis factors, antibodies, lymphokines, enzymes, neurotransmitters, neurotrophic factors, anti-inflammatory agents, and combinations thereof and wherein the system is adapted for implantation into the aqueous and vitreous humor of the eye. The invention also provides for the use of this system in the manufacture of a medicament for the delivery of the biologically active molecule into the aqueous or vitreous humor of the eye. |
