The present invention is directed to compounds which inhibit farnesyl-protein transferase (FTase) and the farnesylation of the oncogene protein Ras. The invention is further directed to chemotherapeutic compositions containing the compounds of this invention and methods for inhibiting farnesyl-protein transferase and the farnesylation of the oncogene protein Ras.
申请公布号
WO9727853(A1)
申请公布日期
1997.08.07
申请号
WO1997US01455
申请日期
1997.01.27
申请人
MERCK & CO., INC.;DINSMORE, CHRISTOPHER, J.;HARTMAN, GEORGE, D.
