Synthetic collagen in triple helical conformation and comprising amino acid chains of repeating trimers of highly populated collagen sequences as well as those sequences wherein the proline or hydroxyproline residue is replaced with a peptoid residue. The invention includes methods of preparing synthetic collagen structures having the triple helix conformation present in collagen from collagen-type polypeptides and poly(peptide-peptoid residue) chains by means of a helix-inducing template.
申请公布号
WO9719106(A3)
申请公布日期
1997.08.07
申请号
WO1996US18521
申请日期
1996.11.18
申请人
THE REGENTS OF THE UNIVERSITY OF CALIFORNIA
发明人
GOODMAN, MURRAY;TAULANE, JOSEPH, P.;FENG, YANGBO;MELACINI, GIUSEPPE