| 发明名称 |
Fibrinogen receptor antagonists |
| 摘要 |
PCT No. PCT/US93/11623 Sec. 371 Date Jun. 1, 1995 Sec. 102(e) Date Jun. 1, 1995 PCT Filed Nov. 29, 1993 PCT Pub. No. WO94/12181 PCT Pub. Date Jun. 9, 1994Novel fibrinogen receptor antagonists of the formula:X-Y-Z-Aryl-A-Bare provided in which the claimed compounds exhibit fibrinogen receptor antagonist activity, inhibit platelet aggregation and are therefore useful in modulating thrombus formation.
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| 申请公布号 |
US5648368(A) |
申请公布日期 |
1997.07.15 |
| 申请号 |
US19950448347 |
申请日期 |
1995.06.01 |
| 申请人 |
MERCK & CO., INC. |
发明人 |
EGBERTSON, MELISSA S.;VASSALLO, LAURA M.;HARTMAN, GEORGE D.;HALCZENKO, WASYL;WHITMAN, DAVID B.;PERKINS, JAMES J.;KRAUSE, AMY E.;IHLE, NATHAN;CLAREMON, DAVID ALAN;HOFFMAN, WILLIAM;DUGGAN, MARK E. |
| 分类号 |
C07D295/08;A61K31/395;A61K31/397;A61K31/40;A61K31/415;A61K31/44;A61K31/4406;A61K31/4409;A61K31/4418;A61K31/4427;A61K31/4433;A61K31/445;A61K31/4465;A61K31/451;A61K31/495;A61P7/02;A61P43/00;C07C255/57;C07C271/22;C07C309/66;C07C311/19;C07D205/04;C07D207/08;C07D211/22;C07D211/26;C07D211/32;C07D211/34;C07D211/46;C07D211/70;C07D213/30;C07D213/71;C07D233/54;C07D233/60;C07D233/64;C07D295/084;C07D295/092;C07D295/096;C07D295/155;C07D401/12;C07D409/12;C07D521/00;(IPC1-7):A61K31/445;C07D211/20;C07D211/98 |
主分类号 |
C07D295/08 |
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