发明名称 Antimycobacterial compounds and method of using same
摘要 The present invention provides a compound having the structure: <IMAGE> wherein R is a branched or unbranched C1-C30 alkyl or alkenyl; or a branched or unbranched C1-C30 alkyl or alkenyl substituted with S, O, N, P, SO2, F, C1, Br, or I, wherein S, O, N, P, or SO2 replaces at least one -CH2-, and F, Cl, Br, or I replaces at least one H. The present invention also provides a pharmaceutical composition comprising the compound above, as well as a method for treating a mycobacterial disease or infection in a subject in need of such treatment by administering to the subject an effective amount of the compound above.
申请公布号 US5648392(A) 申请公布日期 1997.07.15
申请号 US19950386917 申请日期 1995.02.07
申请人 ALBERT EINSTEIN COLLEGE OF MEDICINE OF YESHIVA UNIVERSITY, A DIVISION OF YESHIVA UNIVERSITY 发明人 SACCHETTINI, JAMES;BLANCHARD, JOHN;JACOBS, WILLIAM R.
分类号 C07C57/18;C12N9/02;C30B7/00;(IPC1-7):A61K31/20 主分类号 C07C57/18
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