发明名称 METHOD OF PREPARING AGENT SHOWING ANTITOXIC AND RADIOPROTECTIVE ACTIVITY
摘要 FIELD: medicine. SUBSTANCE: method involves milling cattle spleen, extraction, extract separation and extractant removing. Ethyl alcohol aqueous solution is used as an extractant. Extraction is carried out at simultaneous effect by low-frequency ultrasonic treatment. Extractant is separated by centrifugation. Extractant is preferably removed by alcohol distillation off under vacuum at 45 C, not above. An aqueous extract can be lyophilized. Extractant can contain 65-75% ethanol at weight ratio of spleen and extractant = 1/6-1/3. Ultrasonic frequency is at the range 18-70 kHz at intensity 0.1-2.3 W/cm.. EFFECT: increased yield of the end product, decreased process time. 8 cl, 3 tbl
申请公布号 RU95110154(A) 申请公布日期 1997.06.20
申请号 RU19950110154 申请日期 1995.06.14
申请人 TOMSKIJ GOSUDARSTVENNYJ UNIVERSITET;FARMATSEVTICHESKAJA FIRMA "DARNITSA" 发明人 DYCHKO K.A.;RYZHOVA G.L.;KRAVTSOVA S.S.;KIR'JANOVA N.L.;PASHINSKIJ V.G.;VETOSHKINA T.V.;RATAKHINA L.V.;ZAGORIJ V.A.;STRETOVICH T.N.;ANTOSHCHUK G.G.
分类号 A61K35/28 主分类号 A61K35/28
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