发明名称 |
GENES AND PROTEINS CONTROLLING CHOLESTEROL SYNTHESIS |
摘要 |
The present invention provides isolated nucleic acid sequences which encode a family of HMG-CoA Reductase Degradation (HRD) polypeptides. More particularly, the present invention provides isolated HRD1, HRD2 and HRD3 nucleic acids and the Hrd polypeptides encoded by such nucleic acids, i.e., Hrd1, Hrd2 and Hrd3, respectively. Vectors comprising the nucleic acids are provided. In addition, the present invention provides screening assay related to cholesterol biosynthesis. |
申请公布号 |
WO9707219(A3) |
申请公布日期 |
1997.06.05 |
申请号 |
WO1996IB01161 |
申请日期 |
1996.08.16 |
申请人 |
THE REGENTS OF THE UNIVERSITY OF CALIFORNIA |
发明人 |
RINE, JASPER, D.;HAMPTON, RANDOLPH |
分类号 |
C12N15/09;A61K38/00;A61K48/00;C07K14/39;C07K14/705;C12N9/64;C12Q1/26;C12Q1/68 |
主分类号 |
C12N15/09 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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