发明名称 |
PRODUCTION OF ARYL C-GLYCOSYL COMPOUND AND REAGENT THEREFOR |
摘要 |
PROBLEM TO BE SOLVED: To obtain a reaction reagent giving an aryl C-glycosyl compound in high yield and excellent β-configuration selectivity by compounding a Lewis acid with a silver or mercury salt of trifluoromethanesulfonic acid or trifluoroacetic acid. SOLUTION: The objective aryl C-glycosylating reaction reagent gives an aryl C-glycosyl compound in high yield and excellent β-configuration selectivity by reacting with a sugar and an aryl compound. The reagent can be produced by compounding one or more kinds of Lewis acids (e.g. tin tetrachloride) with one or more kinds of a silver or mercury salt of trifluoromethanesulfonic acid or trifluoroacetic acid at a ratio (Lewis acid : silver or mercury salt of trifluoromethanesulfonic acid or trifluoroacetic acid) of 1:3 to 3:1. The reagent is preferably used in an amount of 1-3 equivalent based on 1 equivalent of the sugar and/or aryl compound. |
申请公布号 |
JPH09143190(A) |
申请公布日期 |
1997.06.03 |
申请号 |
JP19960236044 |
申请日期 |
1996.09.06 |
申请人 |
SANKYO CO LTD |
发明人 |
SATO SUSUMU;KURIBAYASHI TAKESHI;OKAWA NOBUYUKI |
分类号 |
C07H1/00;B01J31/02;B01J31/04;C07B61/00;C07H7/04 |
主分类号 |
C07H1/00 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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