发明名称 REGIOSELECTIVE SYNTHESIS OF 4-CHLORO-2-THIOPHENECARBOXYLIC ACID.
摘要 <p>PCT No. PCT/US93/08613 Sec. 371 Date Jul. 7, 1995 Sec. 102(e) Date Jul. 7, 1995 PCT Filed Sep. 17, 1993 PCT Pub. No. WO94/12505 PCT Pub. Date Jun. 9, 19944-Chloro-2-thiophenecarboxylic acid is made by forming a compound of formula (Ia), disclosed herein, wherein R3 is (C1-C6) alkyl, phenyl, or benzyl; converting the compound to a compound of formula (IVa), disclosed herein, and removing the silyl group R3Si-. The product is useful as an intermediate in making pharmaceutical products.</p>
申请公布号 GR3022396(T3) 申请公布日期 1997.04.30
申请号 GR19960403453T 申请日期 1997.01.29
申请人 PFIZER INC. 发明人 BURGESS, LAURENCE, E.;SCHULTE, GARY, R.
分类号 C07D333/40;C07D;C07D333/38;C07D333/42;C07D409/06;C07F7/08;C07F7/12;(IPC1-7):C07F7/08 主分类号 C07D333/40
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