发明名称 |
ARTERIOSCLEROSIS DEPRESSANT |
摘要 |
<p>9-methyl-3-(1H-tetrazol-5yl) -4H-pyrido Ä1, 2-aÜ pyrimidin-4-one represented by the following formula; <CHEM> and the physiologically-acceptable salts thereof showed to have excellent inhibitory effect on the proliferation of vascular smooth muscle cells and are effective to prevent the occurrence of restenosis after the operation of PTCA, and hence the compounds can be useful for the therapeutic and preventive treatment for arteriosclerosis and other diseases whereto the proliferation of vascular smooth muscle cells is directly concerned.</p> |
申请公布号 |
EP0766963(A1) |
申请公布日期 |
1997.04.09 |
申请号 |
EP19950909975 |
申请日期 |
1995.02.24 |
申请人 |
TT PHARMACEUTICALS, INC. |
发明人 |
TOMIOKA, HISAO;OHSAWA, HIDEFUMI;MOROI, MASAO;KAWASHIMA, T. |
分类号 |
A61K31/517;A61K31/519;C07D471/04;(IPC1-7):A61K31/435 |
主分类号 |
A61K31/517 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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