| 发明名称 |
Controlling bone resorption with pyrroloquinoline quinone (PQQ) and related compounds |
| 摘要 |
PQQ and PQQ-generating compounds inhibit osteoclast cell formation and bone resorption, and those compounds can be used to treat medical conditions characterized by undesired bone resorption. PQQ-phosphonates that target osteoclasts at the bone-mineral interface are particularly useful in this regard.
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| 申请公布号 |
US5616576(A) |
申请公布日期 |
1997.04.01 |
| 申请号 |
US19940274193 |
申请日期 |
1994.07.12 |
| 申请人 |
THE CHILDREN'S MEDICAL CENTER CORPORATION |
发明人 |
HAUSCHKA, PETER V.;GALLOP, PAUL M. |
| 分类号 |
A61K31/4745;A61K31/675;(IPC1-7):A61K31/675;A61K31/44 |
主分类号 |
A61K31/4745 |
| 代理机构 |
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