| 发明名称 |
RIBOZYME THERAPY FOR THE TREATMENT AND/OR PREVENTION OF RESTENOSIS |
| 摘要 |
As an effective therapy for restenosis, this invention provides ribozymes and ribozyme delivery systems useful to inhibit abnormal smooth muscle cell proliferation in vascular tissue. Methods of producing ribozymes and gene therapy utilizing these ribozymes also are provided. The ribozymes are especially targeted to cdc2-kinase PCNA, cyclin B1, lysyl oxidase or an extracellular matrix protein. |
| 申请公布号 |
WO9710334(A2) |
申请公布日期 |
1997.03.20 |
| 申请号 |
WO1996US14838 |
申请日期 |
1996.09.12 |
| 申请人 |
IMMUSOL, INC. |
发明人 |
GOLDENBERG, TSVI;TRITZ, RICHARD |
| 分类号 |
C12N15/09;A61K31/00;A61K31/70;A61K31/7088;A61K35/12;A61K35/76;A61K38/00;A61K48/00;A61P9/00;A61P9/10;C07H21/04;C12N5/10;C12N9/00;C12N15/113 |
主分类号 |
C12N15/09 |
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