SPECIFIC CYCLOOXYGENASE 2 INHIBITOR AND ANTI-INFLAMMATORY AGENT

摘要

A specific cyclooxygenase 2 inhibitor which comprises as the active ingredient 2-(2,6-dichloro-4-hydroxyanilino)-phenylacetic acid represented by formula (1) or its salt, and an anti-inflammatory agent containing the same. The compound inhibits not the cyclooxygenase 1 activity but cyclooxygenase 2 specifically. Thus it scarcely causes any gastrointestinal disorders as the side effect. Further, it is a safe compound having a low toxicity.