发明名称 |
Crystalline amifostine compositions |
摘要 |
The present invention relates to a sterile, stable vacuum dried crystalline amifostine composition and, optionally, pharmaceutically acceptable excipient(s). Typically, the crystalline compositions of the present invention exhibit enhanced stability at temperatures ranging from about 4 DEG C. to about ambient temperature for a period of at least 2 years relative to existing solid vacuum dried amorphous amifostine preparations. The reconstituted compositions of the present invention are suitable for administration to humans as a radio- or chemoprotecting agent.
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申请公布号 |
US5591731(A) |
申请公布日期 |
1997.01.07 |
申请号 |
US19950389386 |
申请日期 |
1995.02.16 |
申请人 |
U.S. BIOSCIENCE, INC. |
发明人 |
KENNEDY, PAUL E.;RAJEWSKI, ROGER A.;BALDONI, JOHN M. |
分类号 |
A61K31/67;A61K9/00;A61K9/19;A61K31/66;A61K31/661;A61K47/02;A61K47/18;A61K47/26;A61P39/00;A61P43/00;C07F9/165;(IPC1-7):A61K31/66 |
主分类号 |
A61K31/67 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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