Oligonucleotides specific for cytokine signal transducer gp1 30 mrna

摘要

The present invention relates to oligonucleotides which are effective inhibitors of disease-associated cellular proliferation and methods of their use. In particular, it relates to the use of oligonucleotides which are substantially complementary to gp130 mRNA sequences. In the form of pharmaceutical compositions, these oligonucleotides are suitable for administration to human subjects for the treatment of abnormal cellular proliferation due to such diseases as cancer, autoimmune disorders and viral infection.