发明名称 Nya acykliska och cykliska amider som aktivatorer för neurotransmitterfrigörande ämnen
摘要 PCT No. PCT/IB95/00189 Sec. 371 Date Feb. 19, 1997 Sec. 102(e) Date Feb. 19, 1997 PCT Filed Mar. 20, 1995 PCT Pub. No. WO95/29909 PCT Pub. Date Nov. 9, 1995This invention relates to compounds of formula (IA), (IB), (IC) or (ID), wherein m, X, Z, R2, R3, R4, R5, R6, R14 and the dotted lines are as defined below, their pharmaceutically acceptable salts, pharmaceutical compositions containing them and methods of using them to treat Alzheimer's disease, age-associated memory impairment, Parkinson's disease and other central nervous system disorders. The claimed compounds have the ability to enhance the release of neurotransmitters such as acetylcholine, dopamine and serotonin. <IMAGE> (IA)
申请公布号 FI964340(A) 申请公布日期 1996.10.28
申请号 FI19960004340 申请日期 1996.10.28
申请人 PFIZER INC. 发明人 VOLKMANN, ROBERT A.;JASYS, VYTAUTAS J.;BRIGHT, GENE M.;VILLALOBOS, ANABELLA;SEYMOUR, PATRICIA A.
分类号 C07D213/56;A61K31/00;A61K31/215;A61K31/341;A61K31/381;A61K31/395;A61K31/415;A61K31/4164;A61K31/4166;A61K31/4178;A61K31/4192;A61K31/4196;A61K31/42;A61K31/44;A61K31/4402;A61K31/4406;A61K31/4409;A61K31/4418;A61K31/4427;A61K31/443;A61K31/4439;A61K31/495;A61K31/4965;A61K31/497;A61K31/505;A61K31/506;A61P25/00;A61P25/16;A61P25/18;A61P25/22;A61P25/28;A61P25/30;A61P43/00;C07C233/06;C07D213/20;C07D231/12;C07D233/76;C07D239/26;C07D241/12;C07D249/04;C07D249/08;C07D261/08;C07D307/16;C07D307/54;C07D333/24;C07D401/06;C07D401/14;C07D405/06;C07D405/14;C07D413/06;(IPC1-7):C07D 主分类号 C07D213/56
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