IMPROVEMENTS TO IMMUNOASSAYS

摘要

A method for detecting the presence of a capture component immobilized on the capture zone of a solid phase for use in an immunoassay or another specific binding pair assay, wherein (a) the capture component is labelled with a label capable of producing a detectable signal directly or indirectly, and the signal is detected before or after the assay is carried out; or (b) after the assay has been carried out, there is performed a further test which comprises contacting the solid phase with an agent that is capable of interacting with the capture component or the captured analyte of the immunoassay or other specific binding pair assay and is also capable of producing a detectable signal directly or indirectly, and detecting the signal. The method enables the elimination of false negative results caused by incomplete or inadequate coating of the capture zone with capture component.