| 摘要 |
A method and composition for treating multidrug resistance in a mammal, in which the composition includes NDGA or an analog of NDGA in accordance with the following formula: <IMAGE> wherein R1 and R2 are independently H, lower alkyl or lower acyl; R3, R4, R5, and R6 are independently H or lower alkyl; R7, R8 and R9 are independently H, hydroxy, lower alkoxy or lower acyloxy; and R10, R11, R12 and R13 are independently H or lower alkyl, in a pharmaceutically acceptable vehicle. The method is particularly suitable for administering an antineoplastic agent, and the composition includes the combination of NDGA, or an analog with such an antineoplastic agent.
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