摘要 |
<p>The cold flow properties of layers of transdermal or transmucosal patches composed of drug/excipient-plasticized polymer adhesives lacking functional groups are maintained at acceptable levels by including a sorptive material in the adhesive-drug/excipient mixture that sorbs a portion of the drug/excipient and thereby prevents the drug/excipient from unduly impairing the cold flow properties of the adhesive.</p> |